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A meta-analysis from 54 epidemiological studies reported that there is a slightly increased relative riskRR1.24of having breast cancer diagnosed in women who are currently using COCsThe observed pattern of increased risk may be due to an earlier diagnosis of breast cancer in COC usersthe biological effects of COCs or a combination of bothThe additional breast cancers diagnosed in current users of COCs or in women who have used COCs in the last ten years are more likely to be localized to the breast than those in women who never used COCs.
After pregnancyGINETTE 35 can be started 21 days after a vaginal deliveryprovided that the patient is fully ambulant and there are no puerperal complicationsAdditional contraceptive precautions willbe required for the first 7 days of tablet takingSince the first postpartum ovulation may precede the first bleedinganother method of contraception should be used in the interval between childbirth and the first course of tabletsLactation is contraindicated with GINETTE 35After a first trimester abortionGINETTE 35 may be started immediatelyin which case no additional contraceptive precautions are required.
Preparations containing oestrogen/progestogen combinations should not be used in the presence of any of the conditions listed belowShould any of the conditions appear for the first time during their usethe product should be stopped immediately.
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