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The serum half-life of lincomycin may be prolonged in patients with severe impairment of renal function compared to patients with normal renal functionIn patients with abnormal hepatic functionserum half-life may be twofold longer than in patients with normal hepatic function.
Lincomycin has been shown to be active against most strains of the following organisms both in vitro and in clinical infectionssee INDICATIONS AND USAGEStaphylococcus aureus Streptococcus pneumoniae.
Diarrhea is a common problem caused by antibacterial which usually ends when the antibacterial is discontinuedSometimes after starting treatment with antibacterialpatients can develop watery and bloody stoolswith or without stomach cramps and fevereven as late as two or more months after having taken the last dose of the antibacterialIf this occurspatients should contact their physician as soon as possible.
There are no studies on the teratogenic potential of lincomycin in animals or adequate and well-controlled studies of pregnant women.
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