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LIORESAL INTRATHECAL is for use in single bolus intrathecal injectionsvia a catheter placed in the lumbar intrathecal space or injection by lumbar punctureand in implantable pumps approved by the FDA specifically for the intrathecal administration of baclofenBecause of the possibility of potentially life-threatening CNS depressioncardiovascular collapseand/or respiratory failurephysicians must be adequately trained and educated in chronic intrathecal infusion therapy.

All patients receiving intrathecal baclofen therapy are potentially at risk for withdrawalEarly symptoms of baclofen withdrawal may include return of baseline spasticitypruritushypotensionand paresthesiasPriapism may develop or recur if treatment with intrathecal baclofen is interruptedSome clinical characteristics of the advanced intrathecal baclofen withdrawal syndrome may resemble autonomic dysreflexiainfectionsepsismalignant hyperthermianeuroleptic-malignant syndromeor other conditions associated with a hypermetabolic state or widespread rhabdomyolysis.

This medication has been prescribed for your current condition onlyDo not use it later for another condition unless your doctor directs you to do soA different medication may be necessary in that case.

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